Visit MBF Bioscience Forum: Primary Sidebar. MBF Bioscience | Stereology and Neuron Morphology Quantitative Analysis When you outsource your stereology analyses to MBF Labs, you get reliable results quickly. We also offer pilot and feasibility studies. Other techniques for obtaining quantitative analyses of cell populations, such as counting cell profiles at the top of each physical section, or using automatic cell detection algorithms, yield inaccurate and biased results. Solve this simple math problem and enter the result. MBF experts and community members will be able to help answer your questions. Results. For this reason, many peer-reviewed journals require or recommend the use of unbiased stereology when quantifying cells or structures. Please note that MBF Bioscience only recommends course. Le seul titre est une information de données et n’affecte pas la cote de sécurité de ce site web. “Stereology provides meaningful quantitative descriptions of the geometry of 3D structures from measurements that are made on 2D images” -Basic Stereology for Biologists and Neuroscientists, 2012, West, M.J., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., page 1. Stereology is the process of sampling and counting material using specific protocols to obtain an estimate of a quantitative parameter, such as number, length, volume, etc. Stereo Investigator uses systematic random sampling (SRS) to obtain a representative sample of the tissue. Stereology Services: Unbiased Quantitative Analyses of Tissue Specimens We realize that there is a growing need for researchers to greatly increase the rate of their data collection. Ask questions and get guidance on most light microscopy techniques and sample preparation for neuron tracing, stereology, and brain mapping. Stereo Investigator Cleared Tissue Edition Stereo Investigator Cleared Tissue Edition is specifically designed for use with images of cleared tissue specimens. A place for the MBF Bioscience community to keep in touch. The company was founded as MicroBrightField, Inc. in 1988 by the father and son team of Dr. Edmund Glaser and Jack Glaser. MBF Bioscience develops software and microscope systems that help neuroscientists discover new information about the brain and the diseases that affect it. Stereo Investigator includes workflows for all of the most popular probes, along with detailed documentation that will guide you through any of the 30+ probes in the program. With an intuitive and task-oriented interface, Stereo Investigator offers researchers more functionality than any other stereology software. University of Vermont, 185 Allen Brook Lane, Suite 101 Stereo Investigator automatically calculates the results for you. Unbiased stereology can seem confusing when you are approaching it for the first time, this site is organized to help simplify the process of picking the best stereological procedure to make unbiased and appropriately precise estimates of what you are looking for. When you call us you will speak with a person - not an automated system. History. Our stereology services are ideal for rigorous analysis required in fields such as drug discovery, biotech research, toxicology, and basic research. These challenges for performing confocal stereology can be overcome by using specialized commercial stereology available from the market leaders MBF Bioscience, Inc. (www.mbfbioscience.com) and Visiopharm (www.visiopharm.com). In order to obtain the accurate results that unbiased stereology is known for, it is important to follow certain practices, described in the literature, during tissue preparation. MBF Bioscience design quantitative imaging software for stereology, neuron reconstruction and image analysis, integrated with the world’s leading microscope systems to empower your research. Stereo Investigator also exports results directly into Microsoft Excel so you can easily sort and further analyze the data. Stereology and Stereo Investigator Webinars MBF Bioscience Inc. 14 videos ... Sign in. MBF Bioscience is a small company that develops software and hardware for bioscience research and biomedical applications. Is the number of cells in a region of interest in experimental subjects different than controls? Definition and History. Request a Quote                       Request More Information. Unbiased stereology is recognized in biological research as the best-practice method for quantitative histology. The Optical Fractionator . Search. It estimates the number, … This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Stereology Services MBF Labs is the world’s leader in providing stereology services. The probe results are calculated to provide an accurate estimate of the counts or measurements for the region(s) of interest as a whole. Unbiased stereology is recognized in biological research as the best-practice method for quantifying biological features in tissue sections. MBF Labs performs unbiased quantitative analyses of tissue specimens for pharmaceutical, biomedical, and research institutions. Our MBF Bioscience staff scientists are uniquely positioned to help you with the transition we are all experiencing. Contact Us                       Learn More About Stereology, MBF Labs’ work was exquisite and was available in a timely fashion. With the main office in Williston, Vermont, USA, the company markets, sells and supports its products from offices on three continents. Additionally, MBF provides you with a host of expert stereological support that includes detailed software workflows within Stereo Investigator, extensive on-line documentation, videos and webinars. Stereo Investigator is the most widely recognized tool for providing reliable stereological analysis. The system first chooses a random starting site within the region of interest - a crucial step for SRS - then directs the motorized XY stage to automatically move at a constant interval to the subsequent sample sites. Sécurité . The resource hub for our customers. ようこそ、MBF Bioscience Japan のウェブサイトへ! Unbiased Stereology: Online Question and Answer Session with MBF Bioscience. Our scientists are available to assist you in every step of the experimental procedure – from designing histological protocols according to the strictest stereological principles, to full analysis and interpretation of experimental data. All of this is available to help guide you through the steps of a stereological study that are briefly outlined below. Design-Based Stereology; Model-Based Stereology; What are you estimating? Dr. Dan Peruzzi, stereology educator and staff scientist at MBF Bioscience, covers both theoretical and practical aspects regarding the use of unbiased stereology to quantify morphological parameters of tissue observed under a microscope or a slide scanner. MBF Bioscience design quantitative imaging software for stereology, neuron reconstruction and image analysis, integrated with the world’s leading microscope systems to empower your research. Read our book about stereology (with a focus on Neuroscience), Read the research paper "Current automatic 3D cell detection methods are not a suitable replacement for manual stereologic cell counting". Develops software and hardware for Bioscience research and technical questions from MBF scientists and technicians collect,... 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